- Sandwich Shop Restaurants, Ironton
- Satellite TV Service, Ironton
- Savings & Loan Associations, Ironton
- Savings Banks, Ironton
- Scrap & Waste Materials, Ironton
- Seafood Restaurants, Ironton
- Secondary Schools, Ironton
- Senior Citizens Service & Health Organizations, Ironton
- Shopping & Shopping Services, Ironton
- Social Services & Welfare, Ironton
- Sod & Sodding Service, Ironton
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- Specialty Stores, Ironton
- State Government, Ironton
- Stone, Ironton
- Stone & Rock Quarry, Ironton - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Stone And Glass Products, Ironton
- Stoves & Furnace Equipment, Ironton - Fittings & Repair Parts
- Submarine Sandwich Restaurants, Ironton
- Surveyor Services, Ironton - Surveying Service
- Surveyors, Ironton
- Swimming Pools, Ironton
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